چالش ها در بیماری پارکینسون / Challenges in Parkinson’s Disease

چالش ها در بیماری پارکینسون Challenges in Parkinson’s Disease

  • 4.0 (1 رای)
  • نوع فایل : کتاب
  • زبان : انگلیسی
  • نویسندگان : Jolanta Dorszewska, Wojciech Kozubski
  • چاپ و سال / کشور: 2016
  • تعداد صفحه : 399

Description

This book is a sum up of knowledge on the genetic factors and neuronal death mechanisms induced by excitotoxic and inflammatory agents. The authors summarize the pathophysiology observed both in patients with Parkinson's disease and in experimental models. The book contains the latest views on drug therapy used in the treatment of parkinsonism and other therapeutic approaches for Parkinson's disease. Parkinson's disease is a common neurological disease and affects 2% population of more than 65 years of age and 5% more than 85 years of age. Pathomechanism of this disease is still not fully understood. Contents Preface 1 Introductory Chapter - Genetic and Biochemical Factors in Parkinson’s Disease 2 Genetics of Parkinson’s Disease: The Role of Copy Number Variations 3 Mechanisms for Neuronal Cell Death in Parkinson’s Disease: Pathological Cross Talks Between Epigenetics and Various Signalling Pathways 4 Inflammation: Role in Parkinson's Disease and Target for Therapy 5 Chronic Inflammation Connects the Development of Parkinson’s Disease and Cancer 6 Is Chronic Systemic Inflammation a Determinant Factor in Developing Parkinson’s Disease? 7 Disorders of Sleep and Motor Control During the Impaired Cholinergic Innervation in Rat – Relevance to Parkinson’s Disease 8 Cognitive Impairment in Parkinson’s Disease: Historical Review, Past, and Present 9 Brain Network Metabolic Changes in Patients with Parkinsonian Tremors 10 Animal Models of Parkinson’s Disease 11 Understanding Pathophysiology of Sporadic Parkinson's Disease in Drosophila Model: Potential Opportunities and Notable Limitations 12 Pharmacotherapeutic Challenges in Parkinson’s Disease Inpatients 13 Clinical and Experimental Cell Therapy in Parkinson’s Disease 14 Cell-Based Therapies for Parkinson’s Disease: Preclinical and Clinical Perspectives 15 Stem Cell Therapy for Parkinson's Disease 16 Surgical Therapy of Parkinson's Disease 17 Neuro-Ophthalmologic Evaluation as a Biomarker for Diagnosis and Progression in Parkinson Disease 18 Possible Treatments of Atypical Parkinsonism 19 The Role of Nurses in Parkinson's Disease
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