Understanding DNA. The molecule and how it works
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : C R Calladine; H R Drew; B F Luisi; A A Travers
- ناشر : Amsterdam : Elsevier Academic Press
- چاپ و سال / کشور: 2004
- شابک / ISBN : 9780121550899
Description
Preface ......................................................................................................... xi Chapter 1 An Introduction to Molecular Biology for Non-Scientists .................................................................. 1 Chapter 2 Why a Helix? .................................................................... 18 Chapter 3 Different Kinds of Double Helix ................................. 39 Chapter 4 Twisting and Curving ..................................................... 64 Chapter 5 Curving in Three Dimensions ...................................... 94 Chapter 6 DNA Supercoiling ........................................................... 116 Chapter 7 The Assembly of DNA into Chromosomes ................ 139 Chapter 8 Specific DNA–Protein Interactions ............................. 173 Chapter 9 Methods Used to Study the Structure of DNA .......... 203 Chapter 10 DNA in Disease, Diagnostics, and Medicine ............ 235 Chapter 11 Cytosine Methylation and DNA Epigenetics ............ 270 Postscript .............................................................................................. 295 Appendix 1: Notes on the Derivation of Some Technical Terms ............................................................... 299 Appendix 2: The Chemical Theory of Base-stacking Interactions in DNA ....................................................... 301 Appendix 3: How to modify Gene Expression Using Anti-sense Oligonucleotides, Ribozymes or Small Interfering-RNA ................................................... 312 Answers to Selected Exercises ............................................................... 323 Index ........................................................................................................... 327
