Appetite and body weight : integrative systems and the development of anti-obesity drugs
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Tim C Kirkham; S J Cooper
- ناشر : Amsterdam ; Boston : Elsevier Academic Press,
- چاپ و سال / کشور: 2007
- شابک / ISBN : 9780123706331
Description
Introduction and overview -- Cortical systems involved in appetite and food consumption -- Nucleus accumbens shell as a model of integrative subcortical forebrain systems regulating food intake -- Hypothalamic neuropeptides and feeding regulation -- Brainstem-hypothalamic neuropeptides and the regulation of feeding -- Gut-brain axis in the control of eating -- Integration of peripheral adiposity signals and psychological controls of appetite -- Brain reward systems for food incentives and hedonics in normal appetite and eating disorders -- Pharmacology of food, taste and learned flavor preferences -- Role of palatability in control of human appetite: implications for understanding and treating obesity -- Learned influences on appetite, food choice, and intake: evidence in human beings -- Gene environment interactions and the origin of the modern obesity epidemic: a novel nonadaptive drift scenario -- Preclinical developments in antiobesity drugs -- Clinical investigations of antiobesity drugs.
Provides a guide to the neural, neurochemical, autonomic and endocrine interrelations which underpin appetite and the controls of food intake and body weight. This book considers psychological aspects such as incentive, preference, liking and palatability, and sets these concepts in their behavioural, pharmacological and neural contexts.
