Handbook of glycomics
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Richard D Cummings; J Michael Pierce
- ناشر : Amsterdam ; Boston : Academic Press/Elsevier
- چاپ و سال / کشور: 2009
- شابک / ISBN : 9780123736000
Description
Sect. I. Glycoconjugate Structural Analysis -- Sect. II. Glycotranscriptomics -- Sect. III. Protein-Glycan Interactions -- Sect. IV. Glycobioinformatics -- Sect. V. Glycomes -- Sect. VI. Disease Glycomes
'This handbook provides the first comprehensive overview of the emerging field of glycomics, defined as the study of all complex carbohydrates in an organism or cell ("the glycome"). Beginning with analytic approaches and bioinformatics, this work provides a detailed discussion of relevant databases, data inegration, and analysis. It then moves on to a discussion of specifc model organism and pathogen glycomes followed by therapeutic approaches to human disorders of glycosylation. Structure and function of glycomes are included along with state-of-the-art technologies and systems approaches to analysis of glycans. * Synthesizes contributions from experts in biology, chemistry, bioinformatics, biotechnology, and medicine * Highlights chapters devoted to chemical synthesis, cancer glycomics and immune cell glycomics * Includes discussions of proteomics, mass spectrometry, NMR, array technology, and transcriptomics analytic approaches