Eukaryotic transcription factors, 5th ed.
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : David S Latchman
- ناشر : Amsterdam ; Boston : Elsevier/Academic Press
- چاپ و سال / کشور: 2008
- شابک / ISBN : 9780123739834
Description
DNA sequences, transcription factors and chromatin structure -- Methods for studying transcription factors -- RNA polymerases and the basal transcriptional complex -- Families of DNA binding transcription factors -- Activation of gene expression by transcription factors -- Repression of gene expression by transcription factors -- Regulation of transcription factor synthesis -- Regulation of transcription factor activity -- Transcription factors and human disease -- Conclusion and future prospects.
Provides coverage of the developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events. This book also covers: the potential of transcription factors as therapeutic targets in human disease; importance of histone modifications; and transcriptional elongation
