AIDS and other manifestations of HIV infection, 4th ed.

List of Contributors iv Preface xv Acknowledgements xvii Dedication xix 1. Epidemiology of HIV and AIDs 1 Patricia L. Fleming 2. Epidemiology of Pediatric HIV Infection 29 Susan M. King, Maru Lou Lindegren and Martha F. Rogers 3. The Genetic Diversity and Global Molecular Epidemiology of HIV 41 Dale J. Hu, Danuta Pieniazek and Timothy D. Mastro 4. Introduction to Retroviruses 53 Stephen P. Goff 5. The Neuropathogenesis of HIV-1 Infection 91 Howard E. Gendelman, Scott Diesing, Harris Gelbard and Susan Swindells 6. Viral Cofactors in the Immune Pathogenisis and Clinical Manifestations of HIV Infection 113 Jeffrey Laurence 7. Virologic and Biologic Features of Human ImmunodeÞciency Virus Type 2 (HIV-2) 127 Jean-Louis SankalŽ and Phyllis J. Kanki 8. Laboratory Detection of Human Retroviral Infection 143 Stanley H. Weiss and Elliot P. Cowan 9. Molecular Diagnostic Techniques and other Tests for Direct Detection of HIV 181 Joseph DeSimone and Roger J. Pomerantz 10. Simian Retroviruses 191 Murray B. Gardner, Maria P. Carlos and Paul A. Luciw 11. ImmunodeÞciency in HIV-1 Infection 259 Ahmad R. Sedaghat and Robert F. Siliciano 12. The Role of Host Genetic Variation in HIV Infection and its Manifestations 279 Richard A. Kaslow, James (Jianming) Tang and M. TevÞk Dorak 13. Care of the Adult Patient with HIV Infection 297 Harold. W. Horowitz and Gary P. Wormser 14. HIV Disease in Women 363 Lisa Ferrigno and Jack A. DeHovitz 15. AIDS Manifestations 381 Sharon Nachman 16. Pulmonary Complications of HIV Infection 399 Krystn R. Wagner and Richard E. Chaisson 17. Mycobacterial Disease in Patients with HIV Infection 417 David Ashkin, Yvonne Hale, Elena Hollender, Michael Lauzardo, Masahiro Narita, Arthur E. Pitchenik, Max SalÞnger and Jerry Jean Stambaugh 18. Neurologic Complications of HIV and AIDS 473 Barbara S. Koppel and Gokhan L. AkÞrat 19. AIDS Psychiatry: Psychiatric and Palliative Care, and Pain Management 529 Mary Ann Adler Cohen and CŽsar A. Alfonso 20. The Gastrointestinal and Hepatobiliary Systems in HIV Infection 569 Donald P. Kotler and Pierre M. Gholam 21. Neoplastic Complications of HIV Infection 589 Paula OÕConnor and David T. Scadden 22. Hematologic Manifestations of HIV Infection 605 John P. Doweiko 23. Cardiac Manifestations in Human ImmunodeÞciency Virus Infection 627 William H. Frishman, Aysha Arshad and Ajay Bansal 24. Renal Manifestations of HIV infection 643 Jonathan A. Winston, Paul E. Klotman and Mary Klotman 25. Skin Manifestations of HIV Infection 655 Miguel Sanchez and Alvin E. Friedman-Kien 26. Ophthalmologic Aspects of HIV Infection 689 Daniel A. Johnson and Douglas A. Jabs 27. General Pathology of HIV Infection 723 James L. Finley, Vijay V. Joshi and Nancy L. Smith 28. Neuropathology of AIDS 763 Umberto De Girolami, Leroy R. Sharer, Dana Gabuzda and Ana Sotrel 29. Infection Control Considerations to Prevent HIV Transmission in Healthcare Settings 791 Linda A. Chiarello, Adelisa L. Panlilio and Denise M. Cardo 30. HIV Era Occupational Exposures and Risks 799 Stanley H. Weiss and Judith D. Leschek 31. Antiretroviral Chemotherapy 827 Robert T. Schooley 32. Discovery and Development of New HIV Medicines 841 Edward P. Garvey, Karen R. Romines and Lawrence R. Boone 33. Toxicities of Antiretroviral Therapy 853 Patrick W. G Mallon, David A. Cooper and Andrew Carr 34. HIV Drug Susceptibility Testing 869 Joseph K. Wong, Davey Smith and Douglas Richman 35. The Analysis of HIV Dynamics Using Mathematical Models 891 Ruy M. Ribeiro and Alan S. Perelson 36. Practical Therapeutics 899 Stephen C. Piscitelli, Scott R. Penzak and Charles Flexner 37. Immune-based Therapies for HIV Infection 917 Maria C. Allende and H. Clifford Lane 38. Immunizations, Vaccine-Preventable Diseases, and HIV Infection 933 Allyn K. Nakashima and Ida M. Onorato 39. Progress in the Development and Testing of HIV Vaccines 959 Marta-Louise Ackers, Bradford N. Bartholow and Timothy D. Mastro 40. The Public Health Response to the HIV Epidemic in the United States 983 Richard J. Wolitski, Robert S. Janssen, David R. Holtgrave and John L. Peterson 41. The Global Impact of HIV and AIDS 1001 Marjorie Opuni and Stefano Bertozzi 42. Nursing Perspectives in the Care of Persons with HIV Infection 1017 Richard L. Sowell, Troy Spicer and Arlene J. Lowenstein 43. Ethical Challenges of the Global AIDS Epidemic 1033 Ronald Bayer