Immunotoxicology of drugs and chemicals. : Volume 1, Principles and methods of immunotoxicology an experimental and clinical approach
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Jacques Descotes
- ناشر : Amsterdam ; Boston : Elsevier
- چاپ و سال / کشور: 2004
- شابک / ISBN : 9780444510938
Description
Immunotoxicology of Drugs and Chemicals: an Experimental and Clinical Approach; Preface; Contents; Definition, history, and scope of immunotoxicology; The immune system: a toxicologist's overview; Health consequences of immunotoxic effects; Mechanisms of immunotoxic effects; Nonclinical evaluation of unexpected immunosuppression; Nonclinical evaluation of unexpected immunostimulation; Nonclinical evaluation of the potential for hypersensitivity; Nonclinical evaluation of the potential for autoimmunity; Regulatory aspects of immunotoxicity evaluation. Nonclinical strategies of immunotoxicity evaluation and risk assessmentClinical immunotoxicology; Immunotherapy of human poisonings; Chemical immunoteratology and developmental immunotoxicology; Immunotoxicity and wildlife; New methods in immunotoxicology; Classification of immunotoxicants; LIST OF ABBREVIATIONS; Index.
This is a review of clinical adverse effects on the human immune system that may occur following drug treatments and chemcical exposures. Current and prospective models and assays that can be used to predict these adverse effects in animal toxicity studies or in human beings are described.
