Diseases of the breast,2nd ed.

Contributing Authors Preface Editors Dedication SECTION I. BREAST ANATOMY AND DEVELOPMENT 1. Breast Anatomy and Development Michael P. Osborne 2. Biochemical Control of Breast Development Robert B. Dickson and Jose Russo SECTION II. DIAGNOSIS AND MANAGEMENT OF BENIGN BREAST DISEASES 3. Physical Examination of the Breast Monica Morrow 4. Management of the Palpable Breast Mass Susan E. Clare and Monica Morrow 5. Management of Disorders of the Ductal System and Infections J. Michael Dixon and Nigel J. Bundred 6. Management of Breast Pain Ian S. Fentiman 7. Abnormalities of the Breast in Pregnancy and Lactation Jeanne A. Petrek 8. Management of Gynecomastia Glenn D. Braunstein 9. Pathology of Benign Breast Disorders Stuart J. Schnitt and James L. Connolly 10. Techniques of Diagnosis of Palpable Breast Masses Roger S. Foster, Jr. SECTION III. BREAST IMAGING AND IMAGE-GUIDED BIOPSY TECHNIQUES 11. Screening for Breast Cancer Robert A. Smith and Carl J. D’Orsi 12. Imaging Analysis of Breast Lesions Daniel B. Kopans 13. Image-Guided Biopsy of Nonpalpable Breast Lesions Luz A. Venta 14. Preoperative Imaging-Guided Needle Localization and Biopsy of Nonpalpable Breast Lesions Daniel B. Kopans and Barbara L. Smith SECTION IV. EPIDEMIOLOGY AND ASSESSING AND MANAGING RISK 15. Epidemiology and Nongenetic Causes of Breast Cancer Walter C. Willett, Beverly Rockhill, Susan E. Hankinson, David J. Hunter, and Graham A. Colditz 16. Inherited Genetic Factors Angela DeMichele and Barbara L. Weber 17. Evaluation and Management of Women with a Strong Family History of Breast Cancer Claudine J. D. Isaacs, Beth N. Peshkin, and Caryn Lerman 18. Prophylactic Mastectomy J. Dirk Iglehart 19. Chemoprevention V. Craig Jordan and Alberto F. Costa SECTION V. PATHOGENESIS OF BREAST CANCER 20. Oncogenes, Suppressor Genes, and Signal Transduction Robert B. Dickson and Marc E. Lippman 21. Autocrine and Paracrine Growth Factors in the Normal and Neoplastic Breast Robert B. Dickson and Marc E. Lippman 22. Animal Models Robert Clarke and Michael D. Johnson 23. In Vitro Models Robert Clarke, Fabio Leonessa, W. Nils Brünner, and Erik W. Thompson 24. Biological Features of Human Premalignant Breast Disease D. Craig Allred and Syed K. Mohsin 25. Control of Invasion and Metastasis W. Nils Brünner, Ross W. Stephens, and Keld Danø SECTION VI. IN SITU CARCINOMA 26. Lobular Carcinoma in Situ Monica Morrow and Stuart J. Schnitt 27. Ductal Carcinoma in Situ and Microinvasive Carcinoma Monica Morrow, Stuart J. Schnitt, and Jay R. Harris SECTION VII. STAGING AND NATURAL HISTORY OF BREAST CANCER 28. Staging of Breast Cancer Jay R. Harris 29. Natural History of Breast Cancer Samuel Hellman and Jay R. Harris SECTION VIII. PATHOLOGY AND BIOLOGICAL MARKERS OF INVASIVE BREAST CANCER 30. Pathology of Invasive Breast Cancer Stuart J. Schnitt and Anthony J. Guidi 31. Estrogen and Progesterone Receptors Richard M. Elledge and Suzanne A. W. Fuqua 32. Prognostic and Predictive Factors Gary M. Clark SECTION IX. PRIMARY TREATMENT OF INVASIVE BREAST CANCER 33. Local Management of Invasive Breast Cancer Monica Morrow and Jay R. Harris 34. Breast Reconstruction Neil A. Fine, Thomas A. Mustoe, and Geoffery Fenner 35. Techniques of Surgery S. Eva Singletary 36. Techniques of Radiation Therapy Allen S. Lichter and Lori J. Pierce 37. Adjuvant Systemic Therapy of Primary Breast Cancer C. Kent Osborne and Peter M. Ravdin 38. Dose-Intensive Chemotherapy Nancy E. Davidson, M. John Kennedy, and Deborah K. Armstrong 39. Treatment of Locally Advanced and Inflammatory Breast Cancer Gabriel N. Hortobagyi, S. Eva Singletary, and Eric A. Strom SECTION X. SPECIAL THERAPEUTIC PROBLEMS 40. Male Breast Cancer William J. Gradishar 41. Phyllodes Tumors Jeanne A. Petrek 42. Paget’s Disease Carolyn M. Kaelin 43. Other Cancers of the Breast Carl Freter 44. Breast Cancer Treatment in Pregnant or Postpartum Women and Subsequent Pregnancy in Breast Cancer Survivors Jeanne A. Petrek and Anne Moore 45. Occult Primary Cancer with Axillary Metastases Alain Fourquet, Anne de la Rochefordière, and François Campana SECTION XI. EVALUATION AFTER PRIMARY THERAPY 46. Evaluation of Patients after Primary Therapy Daniel F. Hayes SECTION XII. MANAGEMENT OF RECURRENT BREAST CANCER 47. Local-Regional Recurrence after Mastectomy or Breast-Conserving Therapy Abram Recht, Steven E. Come, Susan L. Troyan, and Norman L. Sadowsky 48. Treatment of Metastatic Breast Cancer Matthew J. Ellis, Daniel F. Hayes, and Marc E. Lippman SECTION XIII. NEW BREAST CANCER THERAPEUTIC APPROACHES 49. Angiogenesis as a Diagnostic and Therapeutic Target Stephen B. Fox and Adrian L. Harris 50. Immunology and Immunotherapy Martin A. Cheever and Mary L. Disis 51. Biological Therapy Neal Rosen, Laura Sepp-Lorenzino, and Marc E. Lippman SECTION XIV. SITE-SPECIFIC THERAPY OF METASTATIC BREAST CANCER 52. Brain Metastases Patrick Y. Wen and Timothy D. Shafman 53. Epidural Metastases Craig D. McColl and Ronnie J. Freilich 54. Leptomeningeal Metastasis Lisa M. DeAngelis, Lisa R. Rogers, and Kathleen M. Foley 55. Brachial Plexopathy Nathan I. Cherny and Bella Kaufman 56. Ocular Metastases Beryl A. McCormick and David H. Abramson 57. Malignant Effusions Lawrence N. Shulman and David J. Sugarbaker 58. Management of Discrete Pulmonary Nodules Steven J. Mentzer and David J. Sugarbaker 59. Management of Discrete Liver Metastasis Mark S. Talamonti 60. Biology of Bone Metastases Gregory R. Mundy, Theresa A. Guise, and Toshiyuki Yoneda 61. Medical Treatment of Bone Metastases Richard L. Theriault 62. Local Treatment of Bone Metastases Alan D. Aaron and Christine D. Berg SECTION XV. BREAST CANCER IN SPECIAL POPULATIONS 63. Breast Cancer in Older Women Gretchen G. Kimmick and Hyman B. Muss 64. Breast Cancer in Minority Women Jon F. Kerner, Bruce J. Trock, and Jeanne S. Mandelblatt 65. End-of-Life Considerations in Breast Cancer Patients Jane M. Ingham SECTION XVI. ISSUES IN BREAST CANCER SURVIVORSHIP 66. Nursing Care in Patient Management and Quality of Life Karen Hassey Dow and Barbara Hansen Kalinowski 67. Rehabilitation Management: Restoring Fitness and Return to Functional Activity Lynn H. Gerber and Elizabeth M. Augustine 68. Psychosocial Issues and Interventions Julia H. Rowland and Mary Jane Massie 69. Lymphedema Jeanne A. Petrek and Robert Lerner 70. Managing Menopausal Problems Melody A. Cobleigh 71. Reproductive Issues Harold J. Burstein and Eric P. Winer SECTION XVII. MEDICOLEGAL CONSIDERATIONS 72. Medicolegal Aspects of Breast Cancer Evaluation and Treatment R. James Brenner SECTION XVIII. BASIC TOOLS FOR ADVANCING KNOWLEDGE IN BREAST CANCER 73. Techniques in Molecular Biology David Malkin and Hilmi Ozcelik 74. Techniques in Breast Cancer Clinical Trials Rebecca S. Gelman 75. Techniques in the Assessment of Quality of Life May Lin Tao and Patricia A. Ganz 76. Techniques Used in the Assessment of Cost-Effectiveness James A. Hayman and Jane C. Weeks