Joslin's diabetes mellitus,14th ed.

History of diabetes -- Basic mechanisms -- Islets of Langerhans: morphology and its implications -- Insulin biosynthesis and chemistry -- Cell biology of insulin secretion -- Insulin secretion in vivo -- Hormone-fuel interrelationships: fed state, starvation, and diabetes mellitus -- Alterations in protein metabolism in diabetes mellitus -- Molecular aspects of insulin action -- Glucagon -- Peptide growth factors -- Definition and pathogenesis -- Definition, diagnosis and classification of diabetes mellitus and impaired glucose tolerance -- Epidemiology and genetics of diabetes mellitus -- Pathogenesis of insulin-dependent (type I) diabetes mellitus -- Pathogenesis of non-insulin dependent (type II) diabetes mellitus -- Pathology of the pancreas in diabetes mellitus -- Syndromes of extreme insulin resistance -- Secondary forms of diabetes -- Use of animal models in the study of diabetes -- Obesity and lipoprotein disorders -- Obesity -- Treatment of obesity. (cont) Pathophysiology and treatment of lipid disorders in diabetes mellitus -- Treatment of diabetes mellitus -- General approach to the treatment of diabetes -- Education in the treatment of diabetes -- Dietary management -- Psychosocial aspects of diabetes -- Exercise and diabetes -- Principles of insulin therapy -- Iatrogenic hypoglycemia -- Oral antidiabetic agents -- Treatment of the child with diabetes -- Treatment of the elderly with diabetes -- Whole-pancreas and islet-cell transplantation -- Alternative approaches to insulin therapy and recent advances in implantable glucose sensors -- Economic and social costs of diabetes -- Onset of the complications of diabetes -- Epidemiology of late complications of diabetes -- Relationship between metabolic control and long-term complications of diabetes -- Mechanisms of diabetic microvascular complications -- Pathogenesis of macrovascular disease in diabetes -- Pathogenesis of diabetic neuropathy -- Diabetic nephropathy -- Complications: clinical aspects -- Diabetic ketoacidosis and the hyperglycemic, hyperosmolar nonketotic state. (cont) Ocular complications of diabetes mellitus -- Nervous system and diabetes -- Hypertension -- Heart disease in diabetes -- Erectile dysfunction and diabetes -- Infection and diabetes -- Diabetes and pregnancy -- Skin manifestations of diabetes mellitus -- Joint and bone manifestations of diabetes mellitus -- Effects of diabetes mellitus on the digestive system -- Surgery and diabetes -- Foot lesions in patients with diabetes: cause, prevention and treatment -- Vascular disease of the lower extremities in diabetes mellitus: etiology and management -- Hypoglycemia and islet-cell tumors -- Hypoglycemia -- Endocrine tumors of the pancreas.