Pharmaceutical enzymes
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Albert Lauwers; Simon Scharpé
- ناشر : New York : Marcel Dekker,
- چاپ و سال / کشور: 1997
- شابک / ISBN : 9780824793753
Description
Pt. 1. Bioavailability of pharmaceutical enzymes -- Biopharmaceuticl aspects of enzyme absorption -- The endothelium monolayer: barrier to enzyme and drug delivery -- Pt. 2. Tailoring of pharmaceutical enzymes -- Enzyme-albumin conjugates: advantages and problems with targeting -- Acyl enzymes as prodrugs -- Molecular modeling of pharmaceutically important targets -- Pt. 3. Biochemical and pharmacological properties -- The cysteine proteinases from the latex of Carica papaya L -- Bromelain -- Hyaluronidase -- Pancreatic enzyme replacement -- I-asparaginase: an essential antineoplastic drug -- Macrophage-targeted glucocerebrosidase: a therapeutically effective enzyme replacement product for Gaucher Disease -- Deoxyribonuclease I -- Therapeutic protein inhibitors of elastase -- Pt. 4. Standardization and methodology -- Good standardization practices -- Assays.
Pt. 1. Bioavailability of pharmaceutical enzymes --
Biopharmaceuticl aspects of enzyme absorption --
The endothelium monolayer: barrier to enzyme and drug delivery --
Pt. 2. Tailoring of pharmaceutical enzymes --
Enzyme-albumin conjugates: advantages and problems with targeting --
Acyl enzymes as prodrugs --
Molecular modeling of pharmaceutically important targets --
Pt. 3. Biochemical and pharmacological properties --
The cysteine proteinases from the latex of Carica papaya L --
Bromelain --
Hyaluronidase --
Pancreatic enzyme replacement --
I-asparaginase: an essential antineoplastic drug --
Macrophage-targeted glucocerebrosidase: a therapeutically effective enzyme replacement product for Gaucher Disease --
Deoxyribonuclease I --
Therapeutic protein inhibitors of elastase --
Pt. 4. Standardization and methodology --
Good standardization practices --
Assays.
Biopharmaceuticl aspects of enzyme absorption --
The endothelium monolayer: barrier to enzyme and drug delivery --
Pt. 2. Tailoring of pharmaceutical enzymes --
Enzyme-albumin conjugates: advantages and problems with targeting --
Acyl enzymes as prodrugs --
Molecular modeling of pharmaceutically important targets --
Pt. 3. Biochemical and pharmacological properties --
The cysteine proteinases from the latex of Carica papaya L --
Bromelain --
Hyaluronidase --
Pancreatic enzyme replacement --
I-asparaginase: an essential antineoplastic drug --
Macrophage-targeted glucocerebrosidase: a therapeutically effective enzyme replacement product for Gaucher Disease --
Deoxyribonuclease I --
Therapeutic protein inhibitors of elastase --
Pt. 4. Standardization and methodology --
Good standardization practices --
Assays.
