Enhancement in drug delivery
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Elka Touitou; Brian W Barry
- ناشر : Boca Raton : CRC Press
- چاپ و سال / کشور: 2007
- شابک / ISBN : 9780849332036
Description
pt. I. -- Promoted gastrointestinal drug absorption -- Gastrointestinal anatomy, physiology and permeation pathways / Abraham Rubinstein -- Enhancers for enteral delivery of macromolecules with emphasis on surfactants / Biana Godin and Elka Touitou -- Improvement of oral drug absorption by chitosan and its derivatives / Hiraku Onishi and Yoshiharu Machida -- Targeted GI delivery / David R. Friend -- Inhibition of enzymes and secretory transport / Martin Werle and Andreas Bernkop-Schnürch -- Enhanced gastrointestinal absorption lipophilic drugs / Arik Dahan and Amnon Hoffman -- pt. II. Promoted rectal absorption -- Permeation pathways in rectal absorption / Yoshiteru Watanabe -- Cyclodextrins and other enhancers in rectal delivery / Hidetoshi Arima and Kaneto Uekama -- pt. III. Enhancement of buccal and sublingual absorption -- Basic biopharmaceutics of buccal and sublingual absorptions / Priya Batheja, Rashmi Thakur, and Bozena Michniak -- Chemical enhancers in buccal and sublingual absorptions / John D. Smart -- pt. IV. Transdermal enhanced delivery -- The lipid organization in stratum corneum and model systems based on ceramides / Miranda W. de Jager, Maja Ponec , and Joke A. Bouwstra -- Chemical permeation enhancement / Adrian C. Williams and Brian W. Barry -- Vesicular carriers for enhanced delivery through the skin / Elka Touitou and Biana Godin -- Iontophoresis in transdermal delivery / Blaise Mudry, Richard H. Guy, and M. Begoña Delgado-Charro -- Electroporation as a mode of skin penetration enhancement / Michael C. Bonner and Brian W. Barry -- Ultrasound in percutaneous absorption / Joseph Kost and Lior Wolloch -- Combined chemical and electroporation methods of skin penetration enhancement / Michael C. Bonner and Brian W. Barry -- Stratum corneum bypassed or removed / James C. Birchall -- pt. V. Nasal absorption optimization -- Physiological factors affecting nasal drug delivery / Sian Tiong Lim ... [et al.] -- Nasal delivery of peptide drugs / Dennis J. Pillion, John J. Arnold, and Elias Meezan -- pt. VI. Drug absorption from vagina and uterus -- Vagina and uterus as drug-absorbing organs / R. Karl Malcolm ... [et al.] -- Strategies to improve systemic and local availability of drugs administered via vaginal route / Giuseppina Sandri ... [et al.] -- pt. VII. Systemic absorption through the ocular route -- Eye structure and physiological functions / Clive G. Wilson ... [et. al.] -- Drug delivery systems for enhanced ocular absorption / Muhammad Abdulrazik, Francine Behar-Cohen, and Simon Benita -- Ocular penetration enhancers / Indu Pal Kaur and Anupam Batra -- Iontophoresis for ocular drug delivery / Esther Eljarrat-Binstock, Joseph Frucht-Pery, and Abraham J. Domb -- pt. VII. Drug delivery to the central nervous system -- Structure and function of the blood-brain barrier / David J. Begley -- Strategies to overcome the blood-brain barrier / Elena V. Batrakova and Alexander V. Kabanov.
Offering a significant cross-fertilization of ideas across several disciplines, this book provides a comprehensive review of both theoretical and practical aspects of enhancement agents and techniques used for problematic administration routes.