Nanotechnology for cancer therapy

SECTION 1 NANOTECHNOLOGY AND CANCER Introduction and Rationale for Nanotechnology in Cancer Therapy; Fredika M. Robertson and Mauro Ferrari Passive Targeting of Solid Tumors: Pathophysiological Principles and Physicochemical Aspects of Delivery Systems; S. M. Moghimi Active Targeting Strategies in Cancer with a Focus on Potential Nanotechnology Applications; Randall J. Mrsny Pharmacokinetics of Nanocarrier-Mediated Drug and Gene Delivery; Yuriko Higuchi, Shigeru Kawakami, and Mitsuru Hashida Multifunctional Nanoparticles for Cancer Therapy; Todd J. Harris, Geoffrey von Maltzahn, and Sangeeta N. Bhatia Neutron Capture Therapy of Cancer: Nanoparticles and High Molecular Weight Boron Delivery Agents; Gong Wu, Rolf F. Barth, Weilian Yang, Robert J. Lee, Werner Tjarks, Marina V. Backer, and Joseph M. Backer Preclinical Characterization of Engineered Nanoparticles Intended for Cancer Therapeutics; Anil K. Patri, Marina A. Dobrovolskaia, Stephan T. Stern, and Scott E. McNeil Nanotechnology: Regulatory Perspective for Drug Development in Cancer Therapeutics; N. Sadrieh and T. J. Miller SECTION 2 POLYMER CONJUGATES Polymeric Conjugates for Angiogenesis Targeted Tumor Imaging and Therapy; Amitava Mitra, Anjan Nan, Bruce R. Line, and Hamidreza Ghandehari Poly (L-Glutamic Acid): Efficient Carrier of Cancer Therapeutics and Diagnostics; Guodong Zhang, Edward F. Jackson, Sidney Wallace, and Chun Li Noninvasive Visualization of In Vivo Drug Delivery of Paramagnetic Polymer Conjugates with MRI; Zheng-Rong Lu, Yanli Wang, Furong Ye, Anagha Vaidya, and Eun-Kee Jeong SECTION 3 POLYMERIC NANOPARTICLES Polymeric Nanoparticles for Tumor-Targeted Drug Delivery; Tania Betancourt, Amber Doiron, and Lisa Brannon-Peppas Long-Circulating Polymeric Nanoparticles for Drug and Gene Delivery to Tumors; Sushma Kommareddy, Dinesh B. Shenoy, and Mansoor M. Amiji Biodegradable PLGA/PLA Nanoparticles for Anticancer Therapy; Sanjeeb K. Sahoo and Vinod Labhasetwar Poly (alkyl cyanoacrylate) Nanoparticles for Delivery of Anticancer Drugs; R. S. R. Murthy and L. Harivardhan Reddy Aptamers and Cancer Nanotechnology; Omid C. Farokhzad, Sangyong Jon, and Robert Langer SECTION 4 POLYMERIC MICELLES Polymeric Micelles for Formulation of Anticancer Drugs; Helen Lee, Patrick Lim Soo, Jubo Liu, Maok Butler, and Christine Allen PEO-Modified Poly (L-Amino Acid) Micelles for Drug Delivery; Afsaneh Lavasanifar, Xiuo-Bing Xiong, and Hamidreza Montazeri Aliabadi Hydrotropic Polymer Micelles for Cancer Therapeutics; Sang Cheon Lee, Kang Moo Huh, Tooru Ooy, and Kinam Park Tumor-Targeted Delivery of Sparingly-Soluble Anti-Cancer Drugs with Polymeric Lipid-Core Immunomicelles; Vladimir P. Torchilin Combined Cancer Therapy by Micellar-Encapsulated Drug and Ultrasound; Natalya Rapoport Polymeric Micelles Targeting Tumor pH3; Eun Seong Lee and You Han Bae cRGD-Encoded, MRI-Visible Polymeric Micelles for Tumor-Targeted Drug Delivery; Jinming Gao, Norased Nasongkla, and Chalermchai Khemtong Targeted Antisense Oligonucleotide Micellar Delivery Systems; Ji Hoon Jeong, Sun Hwa Kim, and Tae Gwan Park SECTION 5 DENDRITIC NANOCARRIERS Dendrimers as Drug and Gene Delivery Systems; Tae-Il Kim and Jong-Sang Park Dendritic Nanostructures for Cancer Therapy; Ashootosh V. Ambade, Elamprakash N. Savariar, and S. Thai Thayumanavan PEGylated Dendritic Nanoparticulate Carriers of Anti-Cancer Drug; D. Bhadra, S. Bhadra, and N. K. Jain Dendrimer Nanocomposites for Cancer Therapy; Lajos P. Balogh and Mohamed K. Khan SECTION 6 LIPOSOMES Applications of Liposomal Drug Delivery Systems to Cancer Therapy; Alberto A. Gabizon Positively-Charged Liposomes for Targeting Tumor Vasculature; Robert B. Campbell Cell Penetrating Peptide (CPP)-Modified Liposomal Nanocarriers for Intracellular Drug and Gene Delivery; Vladimir P. Torchilin RGD-Modified Liposomes for Tumor Targeting; S. P. Vyas Folate Receptor-Targeted Liposomes for Cancer Therapy; Xiaobin B. Zhao, Natarajan Muthusamy, John C. Byrd, and Robert J. Lee Nanoscale Drug Delivery Vehicles for Solid Tumors: A New Paradigm for Localized Drug Delivery Using Temperature Sensitive Liposomes; David Needham and Ana Ponce SECTION 7 OTHER LIPID NANOSTRUCTURES Nanoemulsions Formulations for Tumor-Targeted Delivery; Sandip B. Tiwari and Mansoor M. Amiji Solid Lipid Nanoparticles for Antitumor Drug Delivery; Ho Lun Wong, Yongqiang Li, Reina Bendayan, Mike Andrew Rauth, and Xiao Yu Wu Lipoprotein Nanoparticles as Delivery Vehicles for Anti-Cancer Agents; Andras G. Lacko, Maya Nair, and Watter J. McConathy DQAsomes as Mitochondria-Targeted Nano-Carriers for Anticancer Drugs; Shing-Ming Cheng, Sarathi V. Boddapati, Gerard G. M. D'Souza, and Volkmar Weissig