Nanoparticle drug delivery systems

1. Nanoparticulate Drug-Delivery Systems: An Overview 1 Deepak Thassu, Yashwant Pathak, and Michel Deleers 2. Nanosuspensions for Parenteral Delivery 33 Barrett E. Rabinow 3. Nanoparticles Prepared Using Natural and Synthetic Polymers 51 Sudhir S. Chakravarthi, Dennis H. Robinson, and Sinjan De 4. Nanofiber-Based Drug Delivery 61 Matthew D. Burke and Dmitry Luzhansky 5. Drug Nanocrystals—The Universal Formulation Approach for Poorly Soluble Drugs 71 Jan Möschwitzer and Rainer H. Müller 6. Lipid-Based Nanoparticulate Drug Delivery Systems 89 Jun Wu, Xiaobin Zhao, and Robert J. Lee 7. Nanoengineering of Drug Delivery Systems 99 Ashwath Jayagopal and V. Prasad Shastri 8. Aerosol Flow Reactor Method for the Synthesis of Multicomponent Drug Nano- and Microparticles 111 Janne Raula, Hannele Eerikäinen, Anna Lähde, and Esko I. Kauppinen 9. Supercooled Smectic Nanoparticles 129 Heike Bunjes and Judith Kuntsche 10. Biological and Engineering Considerations for Developing Tumor-Targeting Metallic Nanoparticle Drug-Delivery Systems 141 Giulio F. Paciotti and Lawrence Tamarkin 11. Biological Requirements for Nanotherapeutic Applications 159 Joseph F. Chiang 12. Role of Nanobiotechnology in the Development of Nanomedicine 173 K. K. Jain 13. Pharmaceutical Applications of Nanoparticulate Drug-Delivery Systems 185 Yashwant Pathak, Deepak Thassu, and Michel Deleers 14. Lipid Nanoparticles (Solid Lipid Nanoparticles and Nanostructured Lipid Carriers) for Cosmetic, Dermal, and Transdermal Applications 213 Eliana B. Souto and Rainer H. Müller 15. Nano-Carriers of Drugs and Genes for the Treatment of Restenosis 235 Einat Cohen-Sela, Victoria Elazar, Hila Epstein-Barash, and Gershon Golomb 16. Ocular Applications of Nanoparticulate Drug-Delivery Systems 271 Annick Ludwig 17. Nanoparticulate Systems for Central Nervous System Drug Delivery 281 Jean-Christophe Olivier and Manuela Pereira de Oliveira 18. Nanoparticles for Gene Delivery: Formulation Characteristics 291 Jaspreet K. Vasir and Vinod Labhasetwar 19. Gastrointestinal Applications of Nanoparticulate Drug-Delivery Systems 305 Maria Rosa Gasco 20. Nanoparticles as Adjuvant-Vectors for Vaccination 317 Socorro Espuelas, Carlos Gamazo, María José Blanco-Prieto, and Juan M. Irache 21. Transdermal Applications of Nanoparticulates 327 Jongwon Shim Index . . . . 339