Bioinformatics methods and protocols
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Stephen Misener; Stephen A Krawetz
- ناشر : Totowa, N.J. : Humana Press
- چاپ و سال / کشور: 2000
- شابک / ISBN : 9780896037328
Description
Introduction: The Role of Genetic Bioinformatics / Michael R. Barnes, Ian C. Gray -- Genetics in the post-genome era--the role of bioinformatics -- Knowledge management and expansion -- Data management and mining -- Genetic study designs -- Physical locus analysis -- Selecting candidate genes for analysis -- Progressing from candidate gene to disease-susceptibility gene -- Comparative genetics and genomics -- Internet Resources for the Geneticist / Michael R. Barnes, Christopher Southan -- Sub-division of biological data on the internet -- Searching the internet for genetic information -- Which web search engine? -- Search syntax: the mathematics of search engine use -- Boolean searching -- Searching scientific literature--getting to 'state of the art' -- Searching full-text journals -- Searching the heart of the biological internet--sequences and genomic data -- Nucleotide and protein sequence databases -- Biological sequence databases--primary and secondary -- Human Genetic Variation: Databases and Concepts / Michael R. Barnes -- Forms and mechanisms of genetic variation -- Databases of human genetic variation -- SNP databases -- Mutation databases -- Genetic marker and microsatellite databases -- Non-nuclear and somatic mutation databases -- Tools for SNP and mutation visualization--the genomic context -- Tools for SNP and mutation visualization--the gene context -- Finding, Delineating and Analysing Genes / Christopher Southan -- The evidence cascade for gene products -- Shortcomings of the standard gene model.
GCG: the wisconsin package of sequence analysis programs (D. D. Womble). Web-based interfaces for the GCG sequence analysis programs (D. D. Womble). Omiga: a PC-based sequence analysis tool (J. A. Kramer). MacVector: integrated sequence analysis for the macintosh (P. A. Rastogi). DNASTAR's lasergene sequence analysis software (T. G. Burland). Pep tool and gene tool: platform-independent tools for biological sequence analysis (D. S. Wishart, P. Stothard, G. H. Van Domselaar). The staden package, 1998 (R. Staden, K. F. Beal, J. K. Bonfield). Building a multiuser sequence analysis facility using freeware (B. Fristensky). Free software in molecular biology for macintosh and MS windows computers (D. Gilbert). Flexible sequence similarity searching with the FASTA3 program package (W. R. Pearson). The use of CLUSTAL W and CLUSTAL X for multiple sequence alignment (A. Aiyar). Phylogenetic analysis using PHYLIP (J. D. Retief). Annotating sequence data using genotator (N. L. Harris). Low cost gel analysis (J. A. Reidler). Computer resources for the clinical and molecular geneticist (Y. Yaron, A. Orr-urtreger). The NCBI: publicly available tools and resources on the web (J. P. Jenuth). Resources at EBI (P. Rodriguez-Tomé). Computer-assisted analysis of transcription control regions: matlnspector and other programs (T. Werner). Computational approaches for gene identification (Gautam B. Singh). Primer3 on the WWW for general users and for biologist programmers (S. Rozen, H. Skaletsky). Using the WWW to supply the molecular biology lab (M. labant, R. Anderson). Network computing: restructuring how scientists use computers and what we get out of them (B. Fristensky). Computing with DNA (L. kari, L. F. Landweber). Detecting biological patterns: the integration of databases, models, and algorithms (G. B. Singh). Design and implementation of an introductory course for computer applications in molecular biology and genetics (S. A. krawetz). The virtual library I: searching MEDLINE (K. Reavie). The virtual library II: science citation index and current awareness services (K. Reavie). The virtual library III: electronic journals, grants, and funding information (K. Reavie).
