Protein Transport into the Endoplasmic Reticulum
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Richard Zimmermann; Ebooks Corporation.
- ناشر : Austin : Landes Bioscience
- چاپ و سال / کشور: 2009
- شابک / ISBN : 9781433711756
Description
1. Post-Targeting Functions of Signal Peptides 2. mRNA Translation on the Endoplasmic Reticulum 3. Translocon Organization in Cells 4. Structure of the Sec61-Complex 5. Sec Complexes in the Yeast ER 6. Th e Role of BiP and Its Co-Chaperones 7. Membrane Protein Biosynthesis at the Endoplasmic Reticulum 8. Membrane Insertion of Tail-Anchored Proteins 9. Human Pathologies of Protein Transport into the Endoplasmic Reticulum
Protein transport into the endoplasmic reticulum (ER) is just one aspect of the general cell biology topic of intracellular protein sorting. This larger picture also includes protein transport into other organelles of the eukaryotic cell (chloroplasts, mitochondria, nucleus, peroxisomes), protein export from bacteria, vesicular transport that delivers to its final destination most of what has been transported into the ER, and protein export from the ER that is associated with protein degradation (termed ERAD). Over the years, protein transport into the ER also has become part of the quest to u