The serotonin receptors : from molecular pharmacology to human therapeutics

Molecular Biology and Genomic Organization of G Protein-Coupled Serotonin Receptors / Wesley K. Kroeze and Bryan L. Roth -- Structure and Function Reveal Insights in the Pharmacology of 5-HT Receptor Subtypes / Richard B. Westkaemper and Bryan L. Roth -- Polymorphic and Posttranscriptional Modifications of 5-HT Receptor Structure: Functional and Pathological Implications / Marilyn A. Davies, Chiao-ying Chang, and Bryan L. Roth -- Strategies for the Development of Selective Serotonergic Agents / Richard A. Glennon -- 5-HT Receptor Signal Transduction Pathways / John R. Raymond, Justin H. Turner, Andrew K. Gelasco, Henry B. Ayiku, Sonya D. Coaxum, John M. Arthur, and Maria N. Garnovskaya -- Agonist-Directed Trafficking of 5-HT Receptor-Mediated Signal Transduction / Kelly A. Berg and William P. Clarke -- Identification of 5-HT₂ and 5-HT₄ Receptor-Interacting Proteins: A Proteomic Approach / Joël Bockaert, Carine Bécamel, Lara Joubert, Sophie Gavarini, Aline Dumuis, and Philippe Marin -- 5-HT Receptor-Associated Proteins (FRAPs): Relevance for Targeting, Trafficking, and Signal Transduction / Zongqi Xia, Douglas J. Sheffler, and Bryan L. Roth -- Cellular and Subcellular Localization of Serotonin Receptors in the Central Nervous System / Laurent Descarries, Virginia Cornea-Hébert, and Mustapha Riad -- Chemical Neuroanatomy of 5-HT Receptor Subtypes in the Mammalian Brain / Guadalupe Mengod, M. Teresa Vilaró, Roser Cortés, Juan F. López-Giménez, Andreu Raurich, and José M. Palacios -- Modulation of the Neuronal Activity and Neurotransmitter Release by 5-HT₁[subscript A] and 5-HT₁[subscript B]/₁[subscript D] Receptors / Pau Celada, Albert Adell, and Francesc Artigas -- Electrophysiology of 5-HT₂[subscript A] Receptors and Relevance for Hallucinogen and Atypical Antipsychotic Drug Actions / Evelyn K. Lambe and George K. Aghajanian -- The Emergence of 5-HT₂[subscript B] Receptors as Targets to Avoid in Designing and Refining Pharmaceuticals / Vincent Setola and Bryan L. Roth -- The 5-HT₃ Receptor / Andrew J. Thompson, Li Zhang, and Sarah C.R. Lummis -- 5-HT₃ and 5-HT₄ Receptors as Targets for Drug Discovery for Dementia / Frank Lezoualc'h and Magali Berthouze -- Electrophysiological Properties of G[alpha][subscript S]-Coupled 5-HT Receptors (5-HT₄, 5-HT₆, 5-HT-- ) / Rodrigo Andrade -- 5-HT₆ Receptors as Targets for the Treatment of Cognitive Deficits in Schizophrenia / Rudy Schreiber, Andrew Sleight, and Marie Woolley --5-HT-- Receptors as Favorable Pharmacological Targets for Drug Discovery / Peter B. Hedlund and J. Gregor Sutcliffe -- Serotonin System Gene Knockouts: A Story of Mice With Implications for Man / Miles Berger and Laurence H. Tecott -- Effects of Serotonin-Related Gene Deletion on Measures of Anxiety, Depression, and Neurotransmission / Anita J. Bechtholt and Irwin Lucki.