Recombinant human erythropoeitin (rhEPO) in clinical oncology : scientific and clinical aspects of anemia in cancer
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : M R Nowrousian
- ناشر : Wein ; New York : Springer
- چاپ و سال / کشور: 2002
- شابک / ISBN : 9783211252239
Description
Contents: Physiology of erythropoiesis.- Biology of EPO.- EPO and EPO-receptor expression in tumor cells and their functional role.- Classification and characterization of anemia in cancer.- Pathophysiology of cancer-related and chemotherapy-induced anemia.- Prevalence, incidence, and treatment of anemia in cancer patients.- Prognostic significance of anemia in cancer chemotherapy.- Incidence and impact of anemia in radiation oncology.- Relationship between anemia and tumor hypoxia.- Tumor hypoxia and therapeutic resistance.- Symptomatology of anemia.- Impact of anemia on organ functions.- Relationship of hemoglobin, fatigue, and quality of life in anemic cancer patients.- Red blood cell transfusions, risks and limitations.- Pharmacology, pharmacokinetics and safety of rhEPO.- rhEPO in anemia associated with multiple myeloma and non-Hodgkin lymphoma.- rhEPO in myeloid disorders.- rhEPO in anemia associated with solid tumors and chemotherapy.- Predictive factors for response of anemia to rhEPO.
Summary: In its Second Edition, this book covers anemia in cancer patients, and treatment with Recombinant Human Erythropoietin (rhEPO). Expanded and updated with new chapters, it describes scientific and clinical aspects of anemia, with diagnostic and therapeutic recommendations on use of rhEPO.
