Pilot study on the use of repeated doses of misoprostol in termination of pregnancy at less than 9 weeks of gestation

Pilot study on the use of repeated doses of misoprostol in termination of pregnancy at less than 9 weeks of gestation

  • نوع فایل : کتاب
  • زبان : انگلیسی
  • مؤلف : O.S. TANG (1), K.S.WONG (2), L.C.H. TANG (2) and P.C. HO (1)
  • چاپ و سال / کشور: 2000

Description

Pregnancy was terminated by repeated doses of vaginal misoprostol in 20 women at a gestational age of less than 9 weeks. The women were given 800 mg of vaginal misoprostol as an initial dose followed by 400 mg of vaginal misoprostol every 3 h for 4 doses. Fourteen women (70%, 95% con¢dence interval: 48^85%) had a complete abortion. Two women (10%) had a missed abortion, and two (10%) had an ongoing pregnancy. Two women (10%) had an incomplete abortion. The interval between the ¢rst dose of misoprostol and the passage of tissue mass was 25.3+34.4 h (median: 15 h).The duration of vaginal bleeding was 23.6+20.4 days (median: 14 days). Side-e،ects were mild and there was no signi¢cant drop in hemoglobin level. Repeated doses of vaginal misoprostol may be an alternative for women who do not want surgical abortion and who live in an area where mifepristone is not available.
Advances in Contraception, 1999; 15: 211^216. #2000Kluwer Academic Publishers. Printed in theNetherlands
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