A software tool for interactive exploration of intrinsic functional connectivity opens new perspectives for brain surgery
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Joachim Böttger , Daniel S. Margulies , Peter Horn , Ulrich W. Thomale , Ilana Podlipsky , Irit Shapira-Lichter , Shereen J. Chaudhry , Christine Szk
- چاپ و سال / کشور: 2011
Description
Background Functional connectivity analysis of resting-state functional magnetic resonance imaging data (fcrs-fMRI) has been shown to be a robust non-invasive method for localization of functional networks (without using specific tasks) and to be promising for presurgical planning. However, in order to transfer the approach to everyday clinical practice, fcrs-fMRI needs to be further validated and made easily accessible to neurosurgeons. This paper addresses the latter by presenting a software tool designed for neurosurgeons for analyzing and visualizing fcrs-fMRI data. Methods A prototypical interactive visualization tool was developed to enable neurosurgeons to explore functional connectivity data and evaluate its usability. The implementation builds upon LIPSIA, an established software package for the assessment of functional neuroimaging data, and integrates the selection of a region-of-interest with the computation and visualization of functionally connected areas. The tool was used to explore data from a healthy participant and eight brain lesion patients. The usability of the software was evaluated with four neurosurgeons previously unacquainted with the methodology,
Acta Neurochir (2011) 153:1561–1572 DOI 10.1007/s00701-011-0985-6
