Evaluation of 99mTc-labeled antibiotics for infection detection
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Fatma Yurt Lambrecht
- چاپ و سال / کشور: 2010
Description
One of the fields of research in nuclear medicine is the development of new radiopharmaceuticals for imaging infection and inflammation in humans. For this development, several antimicrobial peptides, antibiotics, antibiotic peptide and chemotactic peptides, etc., have been radiolabeled with different radionuclides (67Ga, 99mTc, 111In, 18F, 131I, etc.) and their imaging potentials studied. Actually, it is very important to distinguish between infection and inflammation. In this respect, radiolabeled antibiotics have advantages because many of the properties of the ideal infection-specific agent through antibiotics localizes in infection site. In this review, only 99mTclabeled antibiotics are evaluated and discussed.
Ann Nucl Med (2011) 25:1–6 DOI 10.1007/s12149-010-0417-3 Received: 23 July 2010 / Accepted: 18 August 2010 / Published online: 7 October 2010
