99mTc-GSA SPECT analysis was clinically useful to evaluate the effect of interferon in a patient with interferon non-responsive chronic hepatitis C
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Rika Ishii Hitoshi Togashi Akiko Iwaba Chikako Sato Hiroaki Haga Mai Sanjo Kazuo Okumoto Yuko Nishise Jun-itsu Ito Hisayoshi Watanab
- چاپ و سال / کشور: 2011
Description
We describe a 62-year-old woman with advanced chronic hepatitis C who showed no response to low-dose long-term interferon-beta monotherapy (3 MU, three times a week). The interferon monotherapy was continued for 2 years and 9 months. Despite this lack of response to interferon, the patient’s clinical course was good and liver function assessed by 99mTc-galactosyl human serum albumin single photon emission computed tomography (99mTc-GSA SPECT) analysis improved significantly. Improvement of the data obtained by 99mTc-GSA SPECT analysis justified continuation of the treatment. 99mTc-GSA SPECT analysis was clinically useful to evaluate the effect of interferon in a patient with interferon non-responsive chronic hepatitis C, despite a lack of reduction of the ALT level and HCV-RNA titer.
Ann Nucl Med DOI 10.1007/s12149-011-0484-0 Received: 15 December 2010 / Accepted: 23 February 2011
