Spontaneous regression of multicentric pilocytic astrocytoma with CSF dissemination in an adult
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Keiichi Sakai Takahiro Miyahara Keiji Tsutsumi Tomoki Kaneko Mana Fukushima Yuichiro Tanaka Kazuhiro Hongo
- چاپ و سال / کشور: 2011
Description
We present a case of spontaneous regression of multicentric pilocytic astrocytoma with cerebrospinal fluid (CSF) dissemination without neurofibromatosis type 1 (NF1) in an adult, the first such case reported. Magnetic resonance imaging (MRI) showed multiple low signal intensity lesions on T1-weighted images and high signal intensity areas on T2-weighted images in the bilateral thalamus, basal ganglia and midbrain. Contrast-enhanced MRI revealed that small, enhanced lesions were seen in the basal ganglia and the pineal region. Neuroendoscopic biopsy and third ventriculostomy were performed. Intraoperative findings demonstrated CSF dissemination. Histologically, the specimens showed pilocytic astrocytoma. Serial MRIs showed regression of the tumor without any additional treatment. The clinical features of spontaneous regression of pilocytic astrocytoma are discussed.
Brain Tumor Pathol (2011) 28:151–156 DOI 10.1007/s10014-010-0015-z Received: 6 October 2010 / Accepted: 7 December 2010 / Published online: 6 January 2011 The Japan Society of Brain Tumor Pathology 2010
