The effect of age on arteriovenous malformations in children and young adults undergoing magnetic resonance imaging
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Thomas M. O’Lynnger &Wajd N. Al-Holou & Joseph J. Gemmete & Aditya S. Pandey & B. Gregory Thompson & Hugh J. L. Garton & Cormac O. Maher
- چاپ و سال / کشور: 2011
Description
Objective Arteriovenous malformations (AVMs) are the most frequently encountered structural cause of spontaneous intracerebral hemorrhage in childhood, excluding hemorrhages of prematurity. The goal of our study was to examine the relationship between age and AVM prevalence on imaging in children, which to date has not been well described. Methods We queried the electronic and radiographic records of 14,936 consecutive patients aged 25 years or less who had undergone brain magnetic resonance imaging (MRI) at a single institution over an 11-year period to identify those with a cerebral AVM. We collected age, gender, and other demographic characteristics for all patients. For all patients with a cerebral AVM, we recorded the location, size, drainage pattern, Spetzler–Martin grade, medical history, and presence of neurological symptoms. Results Cerebral AVMs were identified in 55 patients (0.37%). The prevalence of AVMs detected on MRI significantly increased with age (p=0.001). AVMs were found in 0.34% of boys (25 of 7,447) and 0.40% of girls (30 of 7,489). AVMs were most commonly identified in the frontal lobes (36%), followed by parietal (20%) and temporal lobes (13%). Sixty percent (n=33) of AVMs were less than 3 cm in size, 35% (n=19) were 3–6 cm in size, and 5.5% (n=3) were greater than 6 cm in size. As for Spetzler–Martin grade of the AVMs, 25.5% were grade I, 18.2% were grade II, 36.4% were grade III, 16.4% were grade IV, and 3.6% were grade V. Conclusions AVMs are seen more frequently on MRI with advancing age in children and young adults.
Childs Nerv Syst (2011) 27:1273–1279 DOI 10.1007/s00381-011-1434-9 Received: 24 January 2011 / Accepted: 8 March 2011 / Published online: 26 March 2011
