Postoperative cerebellar mutism and autistic spectrum disorder
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Erol Tasdemiroًlu & Miktat Kaya & Can Hakan Yldrm & Levent Frat Received:
- چاپ و سال / کشور: 2010
Description
Purpose I read the article “An InsideView of Autism” written by a 44-year-old autistic woman who had a successful international career designing livestock equipment. In this article, she wrote about her life, disease, and experiences as an autistic individual. She stated that “It is interesting that my speech resembled the stressed speech in young children who have had tumors removed from the cerebellum”. Methods In this article, we intend to review and extensively document both postoperative cerebellar mutism and autistic spectrum disorder. Results We reviewed the clinical and neurological findings, etio-pathogenesis, neuroanatomy, mechanisms of development, and similarities between the etio-pathogenesis of both diseases. Conclusions Cerebellar lesions can produce mutism and dysarthria, symptoms sometimes seen in autistic spectrum disorder. In mammals, cerebellar lesions disturb motivated behavior and reduce social interactions, functions that are disturbed in autistic spectrum disorder and cerebellar mutism. The cerebellum and two regions within the frontal lobes are active in certain language tasks. Language is abnormal in autistic spectrum disorder and cerebellar mutism
Childs Nerv Syst (2011) 27:869–878 DOI 10.1007/s00381-010-1316-6 Received: 22 July 2010 / Accepted: 14 October 2010 / Published online: 30 October 2010