Alice-in-Wonderland syndrome—a case-based update and long-term outcome in nine children
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Andrea Weidenfeld & Peter Borusiak
- چاپ و سال / کشور: 2011
Description
Purpose There are some reports of so-called Alice-in- Wonderland syndrome mostly concerning differential diagnosis, association with a variety of infectious diseases and even some case reports on functional imaging. Long-term data are rare. Methods Nine boys aged 6 to 11 years that had been diagnosed with Alice-in-Wonderland syndrome between 2003 and 2008 were contacted for a long-term follow-up study in summer, 2009, with a mean follow-up of 4.6 years. Results At the time of the follow-up study, all children were in good general and mental health. Symptoms of Alice-in-Wonderland syndrome had ceased within weeks or months. In two patients, episodes of metamorphopsia returned after a symptom-free latency of 3 years and 1 year, respectively. Five children had a family history of migraine or epilepsy. In one case, the father was reported to have experienced similar symptoms when he was a child. Conclusion Our follow-up study shows that Alice-in- Wonderland is most likely a benign, self-terminating childhood condition, although occasional recurrences of symptoms are possible.
Childs Nerv Syst (2011) 27:893–896 DOI 10.1007/s00381-011-1400-6 Received: 22 December 2010 / Accepted: 18 January 2011 / Published online: 3 February 2011
