Successful steroid treatment of a patient with autosomal dominant polycystic kidney disease complicated by sarcoidosis
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Yuko Iwasa Junko Arai Michihiro Mitobe Ken Tsuchiya Kosaku Nitta
- چاپ و سال / کشور: 2011
Description
The patient was a 54-year-old woman with autosomal dominant polycystic kidney disease (ADPKD) who developed complicating systemic sarcoidosis. Hypercalcemia and an abrupt increase in serum creatinine levels were observed during the clinical course. Steroid therapy was initiated and produced a distinct improvement in renal function. A kidney biopsy was not feasible because ADPKD is a contraindication for renal needle biopsy. The clinical findings strongly suggested renal disorder secondary to tubulointerstitial nephritis caused by renal sarcoidosis with complicating hypercalcemia. In addition to controlling hypertension and improving the hypercalcemia and dehydration, steroid therapy also improved the renal function in this patient.
Clin Exp Nephrol (2011) 15:442–447, Received: 11 June 2010 / Accepted: 11 January 2011 / Published online: 18 February 2011 Japanese Society of Nephrology 2011
