Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Bozidar M. B. Brkovic & Hari S. Prasad & Michael D. Rohrer & George Konandreas & George Agrogiannis & Dragana Antunovic & George K. B. Sلndor
- چاپ و سال / کشور: 2011
Description
The aim of this study was to investigate the healing of human extraction sockets filled with â- tricalcium phosphate and type I collagen (â-TCP/Clg) cones with or without a barrier membrane. Twenty patients were divided in two groups: (A) â-TCP/Clg non-membrane and (B) â-TCP/Clg + barrier membrane. Clinical examination and biopsies from the grafted sites were collected 9 months later. Bone samples were analyzed using histomorphometry and immunohistochemistry. The horizontal dimension of the alveolar ridge was significantly reduced 9 months after socket preservation in the nonmembrane group. There was bone formation with no significant differences between the two groups in the areas occupied by new bone (A=42.4%; B=45.3%), marrow (A= 42.7%; B=35.7%), or residual graft (A=9.7%; B=12.5%). Immunohistochemistry revealed osteonectin expression in both groups. Both groups demonstrated sufficient amounts of vital bone and socket morphology to support dental implant placement after the 9-month healing period. A future trial to evaluate the alveolar outcomes at an earlier 6- month time point rather than the 9 months used in this study would be of interest.
Clin Oral Invest DOI 10.1007/s00784-011-0531-1 Received: 3 August 2010 / Accepted: 16 February 2011
