Laryngeal involvement in Behcet_s disease—a challenge for treatment
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Menachem Gross & Eldad Ben-Chetrit
- چاپ و سال / کشور: 2011
Description
A patient with severe Behcet_s disease (BD) was referred to our clinic because of severe pharyngolaryngeal involvement. This complication developed under treatment of prednisone and etanercept (Enbrel) 25 mg twice a week. A surgical approach was considered, but following three daily doses of Solu-Medrol (500 mg each) and 300 mg infliximab on the fourth day, the patient improved significantly. This is the first case reporting treatment with infliximab in laryngeal involvement of BD. Although some cases may still require surgical intervention, the therapeutic option of anti-TNF agents, specifically anti-TNF antibodies such as infliximab, may decrease the need for the surgical option.
Clin Rheumatol Received: 31 March 2010 / Accepted: 24 May 2010
