Trypanosoma evansi: therapy with human plasma in infected rats
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Mateus A. Otto & Aleksandro S. da Silva & Lucas T. Gressler & Leticia P. Dall’Agnol & Juliano Bottam & Régis A. Zanette & Daniele C. Oliveira & Silvia
- چاپ و سال / کشور: 2010
Description
The aim of this study was to compare the efficacy of the therapy with human plasma of different blood types and Rh factors in rats infected with Trypanosma evansi. Sixty rats were divided into ten groups of six animals (A-J). Animals from group A (negative control) were not infected and animals from group B (positive control) were inoculated with T. evansi but not treated with plasma. Animals from groups (C-J) were infected with the flagellate and received a curative treatment with 0.5 mL of human plasma with different blood types (A, B, AB, and O) and Rh factors (positive and negative), 48 h after infection. Treatments increased animals’ longevity when compared to group B, although no curative effect was observed since all the rats died within 32 days post-inoculation.
Comp Clin Pathol (2011) 20:139–141 DOI 10.1007/s00580-010-0968-7 Received: 29 September 2009 / Accepted: 7 January 2010 / Published online: 28 January 2010
