Molecular evidence for bovine immunodeficiency virus infection in Iranian sheep and cattle population
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Elahe Tajbakhsh & Gholamreza Nikbakht Borujeni & Hassan Momtaz
- چاپ و سال / کشور: 2010
Description
Bovine immunodeficiency virus (BIV), a member of the lentivirus subfamily of retroviridae, was originally isolated from a dairy cow with persistent lymphocytosis, lymphoid hyperplasia, and prevascular cuffing in the brain. Serological studies indicated that BIV has worldwide distribution, but its prevalence in Iran is not clearly known. In this investigation, we report the detection of proviral DNA sequence of BIV in 300 blood samples of cattle and 150 blood samples of sheep by polymerase chain reaction (PCR) using oligonucleotiode primers specific for the gag gene region of the virus. Blood samples of cattle and sheep were taken from Chaharmahal Bakhtiary province, Iran. According to the PCR results, infection rate in the cattle and sheep population were 60% and 30%, respectively. This is the first report for the presence of BIV in cattle and sheep population of Chaharmahal Bakhtiary province.
Comp Clin Pathol DOI 10.1007/s00580-010-1048-8 Received: 25 November 2009 / Accepted: 8 June 2010