Blood Lipids and Stroke: What More Can We Do Besides Reducing Low-Density Lipoprotein Cholesterol?
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Dominique Deplanque & Pierre Amarenco
- چاپ و سال / کشور: 2011
Description
Statin therapy has became the most important advance in stroke prevention since the introduction of aspirin and blood pressure–lowering therapies. Other lipid-modifying drugs have been less successful in reducing the incidence of stroke, but because of evidence for the use of triglyceridelowering drugs and treatments that raise concentrations of high-density lipoprotein (HDL) cholesterol, further investigations are needed, particularly in patients with an atherogenic dyslipidemia profile (high triglycerides and low HDL cholesterol levels). Furthermore, beyond reducing low-density lipoprotein cholesterol and possibly improving other lipids fractions in patients who are at high risk of stroke, the present review shoes that lipid-modifying drugs might have neuroprotective effects that should also be further explored.
Curr Atheroscler Rep (2011) 13:306–313 DOI 10.1007/s11883-011-0186-z Published online: 25 June 2011
