Variation of Heart-to-Mediastinal Ratio in 123I-mIBG Cardiac Sympathetic Imaging: Its Affecting Factors and Potential Corrections
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Wengen Chen & Qi Cao & Vasken Dilsizian
- چاپ و سال / کشور: 2011
Description
Studies have repeatedly shown the utility of 123I-mIBG cardiac sympathetic imaging for identifying symptomatic heart failure patients most likely to experience adverse cardiac events. Delayed heart-to-mediastinal ratio (H/ M) and washout rate derived from meta-iodobenzylguanidine (mIBG) scintigraphy have been used to monitor response to medical treatment. However, there is great variation of H/M ratio among publications from various institutions. The current article systemically reviews factors that can potentially affect H/M ratio, particularly the acquisition parameters, and proposes new approaches and/or procedures to standardize the imaging procedure and minimize the variation of H/Mamong institutions.
Curr Cardiol Rep (2011) 13:132–137 DOI 10.1007/s11886-010-0157-y Published online: 11 January 2011