Antifungal Dosing in Dialysis and Continuous Renal Replacement Therapy
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Douglas N. Fish
- چاپ و سال / کشور: 2011
Description
Appropriate dosing of antifungal drugs is crucial to achieving favorable outcomes in patients with invasive fungal infections. The use of various types of renal replacement therapy (RRT) in patients with severe acute or chronic renal insufficiency adds another level of complexity to the already challenging use of these drugs. The medical literature provides only a limited number of studies specifically addressing the use of antifungal agents in patients receiving RRT, and there are a number of inherent difficulties in interpreting and applying these studies of drug dosing during RRT to individual patients. This article briefly reviews recent studies examining the dosing of antifungal agents during RRT, and also briefly reviews device-related and drug-related factors that determine the removal of drugs during RRT. Finally, this article summarizes current recommendations for dosing of antifungal agents in patients receiving RRT and highlights areas for future study
Curr Fungal Infect Rep (2011) 5:75–82 DOI 10.1007/s12281-011-0048-8 Published online: 22 March 2011
