Diagnostic Utility of DNA from Aspergillus in Whole Blood Specimens
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Jürgen Lِffler & Oliver Kurzai
- چاپ و سال / کشور: 2011
Description
For several years, PCR-based detection of Aspergillus DNA has been considered a promising tool for the diagnosis of invasive aspergillosis, but its broader implementation has been hampered by a lack of standardization and the uncertain diagnostic accuracy of the wide variety of published protocols. Recently, new attempts have been made to address this problem and define a quality standard for diagnostic Aspergillus PCR. This review summarizes technical aspects of up-to-date protocols, focusing on the recently proposed guidelines of the European Aspergillus PCR Initiative (EAPCRI) for whole blood PCR testing.
Curr Fungal Infect Rep (2011) 5:179–185 DOI 10.1007/s12281-011-0056-8 Published online: 17 May 2011
