Current Approach to the Treatment of Achalasia
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Joseph G. Cheatham & Roy K. H. Wong
- چاپ و سال / کشور: 2011
Description
Achalasia is a primary esophagealmotility disorder characterized by aperistalsis and incomplete or absent relaxation of the lower esophageal sphincter (LES). The cause of the disease remains elusive and there is no intervention that improves the esophageal body function. Currently, treatment options focus on palliation of symptoms by reducing the LES pressure. The most effective and well-tolerated treatments continue to be the laparoscopic Heller myotomy and endoscopic pneumatic dilation; however, newer techniques (eg, peroral endoscopic myotomy and self-expanding metal stents) show promise. Botulinum toxin and pharmacologic therapy are reserved for those who are unable to undergomore effective therapies. Treatment options should be tailored to the patient, using current predictors of outcome such as the patient’s age and post-treatment LES pressures. The aim of this article is to highlight current literature and provide an upto- date approach to the treatment of achalasia.
Curr Gastroenterol Rep (2011) 13:219–225 DOI 10.1007/s11894-011-0190-z Published online: 22 March 2011
