Dual-Acting Angiotensin Receptor–Neprilysin Inhibition
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Julian Segura & Luis M. Ruilope
- چاپ و سال / کشور: 2010
Description
Lowering blood pressure by pharmacologic intervention reduces the incidence of cardiovascular events. Nevertheless, despite the widespread availability of effective antihypertensive medications, the vast majority of hypertensive patients worldwide continue to have inadequate blood pressure control. The development of new antihypertensive drugs could contribute to improving the hypertension control rate, and the blockade of new pathophysiologic pathways involved in blood pressure regulation would offer additional benefits. The dual inhibition of the angiotensin II receptor and neprilysin could provide clinical benefits in a range of cardiovascular diseases, including hypertension and heart failure.
Curr Hypertens Rep (2011) 13:74–78 DOI 10.1007/s11906-010-0166-7 Published online: 3 November 2010
