New Information on the Genetics of Stroke
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : James F. Meschia
- چاپ و سال / کشور: 2010
Description
Ischemic stroke, white matter hyperintensities related to small vessel ischemia, and intracranial aneurysms all show heritability. This review focuses on recent progress in understanding the molecular genetics of these disorders. Also reviewed is recent progress in understanding singlegene disorders in which stroke is a major feature of the phenotype, including CADASIL, CARASIL, hereditary angiopathy with nephropathy, aneurysm and muscle cramps, and Fabry disease and progress in pharmacogenomics as it relates to response to antiplatelet therapy.
Curr Neurol Neurosci Rep (2011) 11:35–41 DOI 10.1007/s11910-010-0155-x Published online: 9 November 2010