Diagnosis and Treatment of Pain in Small-fiber Neuropathy
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Alexandra Hovaguimian & Christopher H. Gibbons
- چاپ و سال / کشور: 2011
Description
Small-fiber neuropathy manifests in a variety of different diseases and often results in symptoms of burning pain, shooting pain, allodynia, and hyperesthesia. Diagnosis of small-fiber neuropathy is determined primarily by the history and physical exam, but functional neurophysiologic testing and skin biopsy evaluation of intraepidermal nerve-fiber density can provide diagnostic confirmation. Management of small-fiber neuropathy depends on the underlying etiology with concurrent treatment of associated neuropathic pain. A variety of recent guidelines proposes the use of antidepressants, anticonvulsants, opioids, topical therapies, and nonpharmacologic treatments as part of the overallmanagement of neuropathic pain. Unfortunately, little data about the treatment of pain specifically in small-fiber neuropathy exist because most studies combine mixed neuropathic pain syndromes in the analysis. Additional studies targeting the treatment of pain in small-fiber neuropathy are needed to guide decisionmaking
Curr Pain Headache Rep (2011) 15:193–200 DOI 10.1007/s11916-011-0181-7 Published online: 1 February 2011
