New Insights into the Biology and Pathobiology of Beta2-Glycoprotein I
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Bill Giannakopoulos & Peyman Mirarabshahi & Steven A. Krilis
- چاپ و سال / کشور: 2010
Description
â2-glycoprotein I (â2GPI) is the major autoantigen in the antiphospholipid syndrome. The central importance of understanding â2GPI physiology from the perspective of the rheumatologist is that it forms the foundation for understanding the pathophysiology underlying autoantibody generation, and the diverse mechanisms by which anti-â2GPI antibodies in complex with â2GPI may predispose an individual to the antiphospholipid syndrome clinical phenotype. This review examines some of the latest novel findings in this area
Curr Rheumatol Rep (2011) 13:90–95 DOI 10.1007/s11926-010-0151-9 Published online: 19 November 2010
