The Role of Phenotyping in Chronic Prostatitis/Chronic Pelvic Pain Syndrome
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Brandon A. Mahal & Jeffrey M. Cohen & Stephen A. Allsop & John B. Moore & Salman F. Bhai & Gino Inverso & Jordan D. Dimitrakoff
- چاپ و سال / کشور: 2011
Description
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a chronic pain syndrome identified by the presence of noninfectious pelvic or perineal pain lasting longer than 3 months. Current diagnoses and treatments for the syndrome solely depend on and target symptoms, respectively. Thus far, the mechanistic disturbances responsible for the pathogenesis of CP/CPPS have remained largely elusive and treatments, and therefore, continue to be ineffective. To move toward successful management and treatment of CP/CPPS, it is necessary to elicit the underlying biological mechanisms responsible for the syndrome. Therefore, a phenotyping system that is able to bridge the gap between current symptom-based diagnosis and future mechanistic approaches to diagnosis and treatment is needed. In this article, we examine current CP/CPPS phenotyping systems, analyze their utility, and make suggestions for changes in clinical approaches to the syndrome that would both promulgate a mechanistic understanding and advance treatment approaches.
Curr Urol Rep (2011) 12:297–303 DOI 10.1007/s11934-011-0196-y Published online: 28 April 2011
