Impact of Chronic Constipation on Health-Related Quality of Life, Work Productivity, and Healthcare Resource Use: An Analysis of the National Health and Wellness Survey
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Shawn X. Sun Marco DiBonaventura Fanta W. Purayidathil Jan-Samuel Wagner Omar Dabbous Reema Mody
- چاپ و سال / کشور: 2011
Description
Background There has been limited research addressing the effects of constipation on work productivity and healthcare resource use. Aims To assess the effect of chronic constipation on health outcomes and healthcare resource use. Methods Using data from the 2007 National Health and Wellness Survey (NHWS), chronic constipation patients (n = 1,430) were propensity score-matched to controls (n = 1,430) on demographic and clinical characteristics. Differences between groups in health-related quality of life (SF-12v2), work productivity and activity impairment, and resource use in the last 6 months were examined. Mediation analyses were conducted in order to determine whether the relationship between constipation and resource use was caused by a reduction in health status. Results Chronic constipation patients reported significantly lower levels of health-related quality of life (physical component summary score: 39.57 vs. 43.73; mental component summary score: 43.19 vs. 47.86, all P-values\0.01) and significantly higher levels of loss of work productivity and activity impairment (absenteeism: 9.08% vs. 5.20%; presenteeism: 29.52% vs. 19.09%; overall work impairment: 33.65% vs. 21.56%; activity impairment: 46.58% vs. 33.90%, all P-values\0.01) compared to the matched controls. Chronic constipation patients also reported significantly more provider (7.73 vs. 5.63) and emergency room visits (0.52 vs. 0.30) in the past 6 months (all P-values\0.01). Mediation analyses suggested that increased resource use among chronic constipation patients were partially a result of reduced health status. Conclusions Compared to matched controls, chronic constipation patients reported greater economic and humanistic burden. Alleviating the humanistic burden associated with constipation may have economic benefits.
Dig Dis Sci DOI 10.1007/s10620-011-1639-5 Received: 19 November 2010 / Accepted: 14 February 2011
