Infliximab-Induced Autoimmune Hepatitis with Successful Switch to Adalimumab in a Patient with Crohn’s disease: The Index Case
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Dahlia A. Goldfeld Elizabeth C. Verna Jay Lefkowitch Arun Swaminath
- چاپ و سال / کشور: 2011
Description
Moderate to severe Crohn’s disease (CD) can be successfully treated with anti-tumor necrosis factor (TNF) a-antagonist agents. These agents, such as infliximab, can cause a spectrum of adverse reactions, some of which demonstrate a class effect, while others are agent-specific. One reported rare complication of infliximab in a patient treated for rheumatoid arthritis, is hepatitis [1]. Herein we report a first case of infliximab-associated autoimmune hepatitis in a patient with Crohn’s disease.
Dig Dis Sci DOI 10.1007/s10620-011-1748-1 Received: 3 January 2011 / Accepted: 3 May 2011
