Evaluation of Growth After Liver Transplantation in Turkish Children
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Masallah Baran Murat Cakir Fatih Unal Gokhan Tumgor Hasan Ali Yuksekkaya Cigdem Arikan Murat Kilic Sema Aydogdu
- چاپ و سال / کشور: 2011
Description
Aims Currently, the main interest in childhood liver transplantation (LT) is to prevent long-term complications and optimize growth. The aim of this study is to analyze (1) nutritional status in the pretransplantation period, and (2) posttransplantation growth and associated factors in children. Patients and Methods Eighty children were included in the study. Height (ZH) and weight (ZW) Z scores were calculated before transplantation and postoperatively at the 6th month and 1st, 2nd, 3rd, 4th, and 5th year. Results Patients’ ZH and ZW scores at LT were -1.6 ± 1.3 and -1.5 ± 1.4, respectively. Both ZH and ZW scores increased after LT, especially in the first 6 months, and then continued to rise gradually. Both reached beyond -1 Z score at 2nd year and -0.5 at 4th year. Age, primary diagnosis, total steroid dose (\1,000 mg), and absence of rejection episodes had positive impact on posttransplantation growth, whereas gender, immunosuppression type, surgical complications, and presence of tumor had no impact on posttransplantation growth. Age at time of LT was negatively correlated with ZW score at 5th year (P = 0.02, r = -0.43). Both ZW and ZH scores at time of LT were positively correlated with ZW and ZH scores and negatively correlated with DZW and DZH scores at 5th year. Conclusions LT is not only a modern, life-saving treatment technique but also an efficient method of facilitating growth, an indispensable component of childhood and the best indicator of health.
Dig Dis Sci DOI 10.1007/s10620-011-1727-6 Received: 7 March 2011 / Accepted: 15 April 2011
