Obstructive sleep apnea in Treacher Collins syndrome
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Harriet Akre Britt طverland Pamela A ° sten Nina Skogedal Ketil Heimdal
- چاپ و سال / کشور: 2011
Description
The aim of the present study was to investigate the prevalence of obstructive sleep apnea syndrome (OSAS) among the Norwegian population with Treacher Collins syndrome (TCS). A secondary aim was to establish whether TCS phenotype severity is associated with OSAS severity. A prospective case study design was used. Individuals who were 5 years old and above with a known diagnosis of TCS in Norway were invited to participate in a study. The study included genetic testing, medical and dental examinations and polysomnography. All participants demonstrated disturbed respiration during sleep; 18/19 met the diagnostic criteria for OSAS. Subjectively evaluated snoring was not a reliable predictor of OSAS. We found no significant association between TCS phenotype severity and the severity of OSAS. OSAS is common in TCS, but there is no association with the phenotype severity. Individuals diagnosed with TCS must undergo sleep studies to identify the presence of OSAS.
Eur Arch Otorhinolaryngol,Received: 16 March 2011 / Accepted: 11 May 2011 The Author(s) 2011. This article is published with open access at Springerlink.com
