GEIRA: gene-environment and gene–gene interaction research application
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Bo Ding Henrik Ka¨llberg Lars Klareskog Leonid Padyukov Lars Alfredsson
- چاپ و سال / کشور: 2011
Description
The GEIRA (Gene-Environment and Gene– Gene Interaction Research Application) algorithm and subsequent program is dedicated to genome-wide geneenvironment and gene–gene interaction analysis. It implements concepts of both additive and multiplicative interaction as well as calculations based on dominant, recessive and co-dominant genetic models, respectively. Estimates of interactions are incorporated in a single table to make the output easily read. The algorithm is coded in both SAS and R. GEIRA is freely available to non-commercial users at http://www.epinet.se. Additional information, including user’s manual and example datasets is available online at http://www.epinet.se.
Eur J Epidemiol (2011) 26:557–561 DOI 10.1007/s10654-011-9582-5 Received: 14 June 2010 / Accepted: 7 April 2011 / Published online: 26 April 2011
