Burn scar pleomorphic sarcoma—case report
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Daniel Francisco Mello & Stephanie Carneiro & Karen Chicol Gonçalves & Douglas Jorge
- چاپ و سال / کشور: 2011
Description
Malignant transformation in burn scars was formally described by Jean-Nicholas Marjolin in 1828, although there are reports that this phenomenon had been first noted by Celsus in the first century A.D. The term Marjolin’s ulcer (MU) is used to denote the malignancies, predominantly squamous cell carcinomas, which develop in scars and chronic wounds [1–3]. The burned area, especially those which healed by secondary intention, is at risk of injury by daily activities because their coverage differs from normal skin, with reduced elasticity and hydration. The main factors that predispose to malignant transformation are: time of evolution, injury and constant irritation, chronic infection, poor hygiene habits, and environmental factors [1–3]. The percentage of scars that progress to malignancy is estimated at 2%, where squamous cell carcinoma is the most common histological type, followed by basal cell carcinoma and melanoma. Sarcomas, however, are rarely described [4–8]. The aim of this paper is to report a case of undifferentiated pleomorphic sarcoma in a burn scar treated at our service.
Eur J Plast Surg DOI 10.1007/s00238-011-0598-6 Received: 10 December 2010 / Accepted: 17 May 2011