Diagnostic performance of 320-detector CT coronary angiography in patients with atrial fibrillation: preliminary results
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Lei Xu & Lin Yang & Zhanming Fan & Wei Yu & Biao Lv & Zhaoqi Zhang
- چاپ و سال / کشور: 2010
Description
Objective To evaluate the feasibility, diagnostic accuracy, and radiation dose of CT coronary angiography (CTCA) in patients with atrial fibrillation (AF) using 320-detector CT. Methods Thirty-seven patients with persistent AF and suspected coronary artery disease (CAD) were enrolled. All patients underwent both 320-detector CTCA and conventional coronary angiography (CCA). CT image quality and the presence of significant (≥50%) stenosis were evaluated by two radiologists blinded to the results of CCA. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated using CCA as the reference standard. Differences in detection of coronary artery stenosis between 320-detector CTCA and CCA were evaluated with McNemar’s test. Patient radiation dose was calculated by multiplying dose length product by conversion coefficient of 0.017. Results In total 474 evaluated coronary segments, 459 (96.8%) segments were diagnostically evaluable. On persegment analysis, sensitivity, specificity, PPV and NPV were 90.0% (18 of 20), 99.3% (436 of 439), 85.7% (18 of 21) and 99.5% (436 of 438). No significant difference was found between 320-detector CTCA and CCA on the detection of significant stenosis (P=1.000). Effective doses of 320-detector CTCA was 13.0±4.7 mSv. Conclusion 320-detector CTCA is feasible and accurate in excluding CAD in patients with AF.
Eur Radiol (2011) 21:936–943 DOI 10.1007/s00330-010-1987-0 Received: 28 June 2010 / Revised: 13 August 2010 / Accepted: 15 September 2010 / Published online: 14 December 2010
