Comparison of semi-automated and manual methods to measure the volume of liver tumours on MDCT images
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Léna Dubus & Mathilde Gayet & Magaly Zappa & Liliane Abaleo & Aurélie De Cooman & Guillaume Orieux & Valérie Vilgrain
- چاپ و سال / کشور: 2010
Description
Objective To retrospectively compare semi-automated and manual volume measurements of malignant liver tumours and inter- and intra-observer variability using commercially available software. Methods This study was performed on 60 consecutive patients with untreated liver metastases (30) and HCCs (30), i.e. 92 lesions (49 metastases, 43 HCCs) using hepaticMDCT. Lesion volumes were manually measured independently by two radiologists and semi-automatically by the same two radiologists and a technician. Those measurements were repeated on 20 patients (10 metastases and 10 HCCs) a week later. An independent operator timed all the measurements. Using the Spearman correlation coefficient and Bland-Altman plots, statistical analyses were performed. Results Liver lesion volumes obtained with semi-automated and manual methods were well correlated (Spearman, r=0.98 and 0.91). Their agreement was high for intraobserver measurements with the semi-automated method (Spearman, r=0.91 and 0.94). The agreement was lower for inter-observer measurements with both methods (Spearman, r=0.87 for semi-automated and 0.91 for manual). The semi-automated method significantly reduced the post-processing duration (23s±19s vs. 33s±11s, p value <0.0001). Conclusion In our study, semi-automated volume analysis of malignant liver tumours correlated well with the manual method. Furthermore, the semi-automated volume analysis was significantly quicker.
Eur Radiol (2011) 21:996–1003 DOI 10.1007/s00330-010-2013-2 Received: 20 July 2010 / Revised: 8 September 2010 / Accepted: 3 October 2010 / Published online: 5 December 2010
