Feasibility of diffusion tensor imaging (DTI) with fibre tractography of the normal female pelvic floor
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : F. M. Zijta &M. Froeling & M. P. van der Paardt & M. M. E. Lakeman & S. Bipat & A. D. Montauban van Swijndregt & G. J. Strijkers & A. J. Nederveen & J
- چاپ و سال / کشور: 2011
Description
Objectives To prospectively determine the feasibility of diffusion tensor imaging (DTI) with fibre tractography as a tool for the three-dimensional (3D) visualisation of normal pelvic floor anatomy. Methods Five young female nulliparous subjects (mean age 28±3 years) underwent DTI at 3.0T. Two-dimensional diffusion-weighted axial spin-echo echo-planar (SP-EPI) pulse sequence of the pelvic floor was performed, with additional T2-TSE multiplanar sequences for anatomical reference. Fibre tractography for visualisation of predefined pelvic floor and pelvic wall muscles was performed offline by two observers, applying a consensus method. Three eigenvalues (l1, l2, l3), fractional anisotropy (FA) and mean diffusivity (MD) were calculated from the fibre trajectories. Results In all subjects fibre tractography resulted in a satisfactory anatomical representation of the pubovisceral muscle, perineal body, anal - and urethral sphincter complex and internal obturator muscle. Mean FA values ranged from 0.23±0.02 to 0.30±0.04,MD values from 1.30±0.08 to 1.73± 0.12×10-³mm²/s. Muscular structures in the superficial layer of the pelvic floor could not be satisfactorily identified. Conclusions This study demonstrates the feasibility of visualising the complex three-dimensional pelvic floor architecture using 3T-DTI with fibre tractography. DTI of the deep female pelvic floor may provide new insights into pelvic floor disorders.
Eur Radiol (2011) 21:1243–1249 DOI 10.1007/s00330-010-2044-8 Received: 1 September 2010 / Revised: 18 October 2010 / Accepted: 3 November 2010 / Published online: 1 January 2011
