CT of the hips in the investigation of protrusio acetabuli in Marfan syndrome. A case control study
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Rigmor Lundby & Eva Kirkhus & Svend Rand-Hendriksen & John Hald & Are Hugo Pripp & Hans-Jّrgen Smith
- چاپ و سال / کشور: 2011
Description
Objectives To establish the prevalence of protrusio acetabuli (PA) in adults fulfilling the Ghent criteria for Marfan syndrome (MFS), and in a normal adult population. Methods 105 adults with probable MFS and 107 controls were included. CT of the hips was obtained. A qualitative assessment of PA was performed. A new method for estimating the degree of PA was introduced with measurement of the parameter CWD (circle-wall distance). Results were compared to an alternative method based on MRI [1]. Results 87 of the study group fulfilled the Ghent criteria of MFS (Ghent positives), and 18 did not (Ghent negatives). PA was diagnosed qualitatively in 74.7% of Ghent positive persons, in 27.8% of Ghent negative persons, and in 3.7% of the controls. CWD was significantly different between the three groups (p<0.001). A slight but significant gender difference was found in Ghent positive persons only. The alternative method did not differentiate between the groups with respect to PA, but showed a significant difference between genders. Conclusions PA was found significantly more often in MFS persons than in controls. Our method was found to be robust and highly reproducible, giving a direct measurement of pelvic protrusion irrespective of pelvic shape.
Eur Radiol (2011) 21:1485–1491 DOI 10.1007/s00330-011-2073-y Received: 28 September 2010 / Revised: 10 December 2010 / Accepted: 6 January 2011 / Published online: 14 February 2011
